Note

Oguchi disease is a very rare disorder that has been reported more frequently in Japanese individuals.

Mutation:

• SAG → Arrestin
• GRK1 → Rhodopsin kinase

Clinical findings:

Mizuo–Nakamura phenomenon on fundus examination: the retina appears normal in darkness but develops a yellowish, bright iridescent appearance under illumination.

Fill in the Blanks

In Oguchi disease, the retina develops a yellowish iridescent appearance in .

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